N-Desmethyl-loperamide

N-Desmethyl-loperamide

N-Desmethyl-loperamide designer drug synthetic opiate, analog Loperamide with all its properties. N-Desmethyl-loperamide is produced on modern chemical equipment, which makes this opiate very high-quality and clean. This chemical is intended for chemical research and for no other purpose.

N-Desmethyl-loperamide

Synonyms

  • dLop
  • R 20905

IUPAC

4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-1-piperidinebutanamide

Formula

C28H31ClN2O2

Molecular weight

463.0 g/mol

CAS

 66164-07-6

Appearance

Powder

Purity

≥ 98%

Restriction

Regulated

Loperamide is a synthetic opiate that efficiently and selectively activates the μ opioid receptors Ki = 0.16 nM, exclusively at the periphery. N-Desmethyl-loperamide (dLop) is the main metabolite of loperamide. dLop is a substrate of an ATP-dependent outflow conveyor, P-glycoprotein. As a result, both the initial compound and the mapping of metabolites, limited by passage through the blood, can be analyzed by various methods.

Storage conditions: in a dry and cool place. The terms para-chloro N-Desmethyl-loperamide can last up to 2 years under proper storage conditions.

Price:

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